Platelet Function Disorders In Children

Platelets are cells that circulate in the blood stream and help the blood to clot. When a child has a platelet function disorder, their blood may not be able to clot normally which results in an increased risk of bleeding.

  • Platelet function disorders may be acquired as a result of an external factor like another illness or medication.
  • Platelet function disorders can also be caused by a genetic mutation, in which case the children are born with the disorder.

Platelet Function Disorder Treatment

Children with all types of abnormal platelet function are treated through the Platelet Function Disorders Program within the Blood Disorders Center.

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What are the symptoms of platelet function disorders?

The most common symptoms of platelet function disorders are:

  • purpura (purple color of the skin after blood has leaked under it forming a bruise, often from no known trauma)
  • petechiae (tiny red dots under the skin that are a result of very small bleeds into the skin)
  • nosebleeds
  • bleeding in the mouth and/or in and around the gums
  • blood in vomit, urine or stool
  • bleeding in the head (most dangerous symptom that can be life-threatening, usually prompted by head trauma)

How are platelet function disorders diagnosed?

Platelet function disorders can be identified through the following tests:

  • careful review of your child’s history, including medications
  • complete blood count
  • examination of the blood under the microscope by an expert pediatric hematologist
  • blood tests of platelet function
  • genetic tests

What are platelet function disorder treatment options?

If your child has a platelet function disorder, these treatments may be considered:
  • A number of medicines can help reduce the risk of bleeding.
  • Platelet transfusions can be given if necessary.
  • In the most severe cases, bone marrow transplantation is an option.

Caring for a child with a platelet function disorder

Preventing serious bleeding is a very important aspect of care. Parents should consider:

  • padding your child’s crib
  • restricting certain contact sports and rough play
  • avoiding medications that may interfere with platelet function and may cause bleeding, including aspirin, ibuprofen, Motrin, Advil, naproxen, Naprosyn, Aleve, and more
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